Catabolite control protein A <p>Catabolite control protein A is a LacI family global transcriptional regulator found in Gram-positive bacteria. CcpA is involved in repressing carbohydrate utilization genes [ex: alpha-amylase (amyE), acetyl-coenzyme A synthase (acsA)] and in activating genes involved in transporting excess carbon from the cell [e.g. acetate kinase (ackA), alpha-acetolactate synthase (alsS)]. Additionally, disruption of CcpA in <taxon tax_id="1404">Bacillus megaterium</taxon>, <taxon tax_id="1288">Staphylococcus xylosus</taxon>, <taxon tax_id="1582">Lactobacillus casei</taxon> and <taxon tax_id="1589">Lactobacillus pentosus</taxon> also decreases growth rate, which suggests CcpA is involved in the regulation of other metabolic pathways.</p>